Neuropathy, in particular peripheral neuropathy, is a progressive degenerative nerve condition that affects approximately 300 million people globally. It is characterized by symptoms such as tingling (paraesthesia), numbness, pain, temperature sensitivity, and muscle weakness in the hands and feet and can spread throughout the body. One of the most common questions asked by those who are affected is “Can B12 help with neuropathy to alleviate its symptoms?”
Let’s explore this question, delve into the science behind B12, and understand how it may play a role in neuropathy treatment.
Neuropathy, often called peripheral neuropathy, isn’t a single condition but rather a group of conditions arising from nerve damage in the peripheral nervous system. This system comprises nerve structures beyond the brain and spinal cord that communicate with the rest of the body. When these nerves are damaged communication begins to break down. Damage can occur from many sources, including:
So now we know a little more about neuropathy and its causes let’s move on to B12.
Vitamin B12, also known as cobalamin, is a water-soluble nutrient that’s crucial for the production and maintenance of myelin, the protective sheath around nerves that allows for efficient signal transmission.
When B12 levels are insufficient, this protective coating can deteriorate, leading to improper nerve function and ultimately nerve damage. This connection explains why Vitamin B12 deficiency is strongly associated with neuropathy symptoms.
Sufficient amounts of B12 help keep your body’s blood cells healthy and enable it to create DNA as necessary while simultaneously controlling the regulation of fatty acid and amino acid metabolism.
When you’re deficient in B12, not only do the nerves suffer but the body also struggles to produce sufficient healthy red blood cells to carry oxygen to tissues and nerves, compounding the problem and often leading to anemia.
Vitamin B12 is present in foods of animal origin, including meat, fish, poultry, eggs and dairy products. Plant foods are not a natural source of vitamin B12, however, fortified yeasts and breakfast cereals are available as a non-animal source.
B12 is also a part of the larger B vitamins group, including B-1 and B-6 which all offer support for the nervous system function.
In cases of neuropathy caused by vitamin 12 deficiency, supplementation has been seen to improve symptoms. Let’s look at some of the evidence behind this:
Studies have found that correcting a Vitamin B12 deficiency can alleviate neuropathy symptoms, particularly in patients with diabetic neuropathy and chemotherapy-induced neuropathy. For example, a 2016 study highlighted how high doses of Vitamin B12, alongside other B vitamins, helped reduce pain and improve nerve conduction in diabetic patients.
Diabetic neuropathy is one of the most common forms of peripheral neuropathy. For individuals with diabetes, nerve damage often arises as a result of prolonged high blood sugar levels. Research suggests that B12 supplementation may protect against nerve damage by improving nerve regeneration and function. In fact, some patients have seen improvement in pain levels and mobility after B12 therapy.
B12 supplementation may also be beneficial for patients with autoimmune conditions that cause nerve damage. Because autoimmune conditions can prevent proper absorption of B12, these patients are at increased risk of deficiency. In these cases, replenishing B12 can help stabilize nerve function.
Chemotherapy drugs, while effective at targeting cancer, often cause nerve damage, leading to neuropathy. Patients undergoing chemotherapy have found relief through B12 supplementation as well. One study noted that B12 supplements, along with folic acid, improved symptoms of neuropathy in patients treated with certain chemotherapy agents.
In many cases, Vitamin B12 supplementation can help alleviate neuropathy-related pain. Although quite rare, B12 may aid in repairing the myelin sheath depending on the underlying cause of the neuropathy.
Not everyone who has neuropathy is B12 deficient. Its role in promoting tissue regeneration and enhancing nerve function can be beneficial for some individuals. as a preventative measure to protect against long-term nerve damage:
It's important to consult your doctor before adding any supplements, including Vitamin B12, to your neuropathy treatment plan. Your healthcare provider can help determine whether a B12 supplement is right for you or if you can increase your intake through dietary changes. If a significant deficiency is suspected, your doctor may also recommend testing your B12 levels. For those with severe deficiencies, B12 injections may be an option to restore levels effectively.
In addition to B12, other B vitamins can play a role in neuropathy treatment. Vitamin B1 (thiamine) may help reduce pain and inflammation and protect against cellular damage. Vitamin B6 supports the protective coverings on nerve endings, but it should be taken cautiously, as excessive doses can contribute to further nerve damage. Your doctor may also advise you on specific foods to avoid if you have neuropathy, as certain dietary choices can affect nerve health.
If you’re experiencing symptoms of neuropathy, MINT STL is here to provide comprehensive, personalized treatment tailored to your needs. If you have any questions about the role of Vitamin B12 in managing neuropathy, reach out to us today. Call us to request an appointment or use our online booking system.
